Title : Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells.

Pub. Date : 2008 May 9

PMID : 18356544






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Overexpression of Abcg2 results in an increased ability to consume hydrogen peroxide and is associated with increased levels of alpha-glutathione reductase protein expression. Hydrogen Peroxide ATP binding cassette subfamily G member 2 (Junior blood group) Mus musculus
2 Importantly, overexpression of Abcg2 also conferred a cell survival benefit following exposure to hydrogen peroxide. Hydrogen Peroxide ATP binding cassette subfamily G member 2 (Junior blood group) Mus musculus