Title : The role of chloride anion and CFTR in killing of Pseudomonas aeruginosa by normal and CF neutrophils.

Pub. Date : 2008 Jun

PMID : 18353929






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Chloride anion is essential for myeloperoxidase (MPO) to produce hypochlorous acid (HOCl) in polymorphonuclear neutrophils (PMNs). Chlorides myeloperoxidase Homo sapiens
2 We previously reported that neutrophils from CF patients are defective in chlorination of ingested bacteria, suggesting that the chloride channel defect might impair the MPO-hydrogen peroxide-chloride microbicidal function. Chlorides myeloperoxidase Homo sapiens