Pub. Date : 2008 Apr 9
PMID : 18345677
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Type I IPP isomerase (IDI-1) utilizes a divalent metal in a protonation-deprotonation reaction; whereas, the type II enzyme (IDI-2) requires reduced flavin. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |
| 2 | These studies indicate that the irreversible inhibitors inactivate the reduced flavin required for catalysis by electrophilic alkylation and are consistent with a protonation-deprotonation mechanism for the isomerization catalyzed by IDI-2. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |