Title : Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase.

Pub. Date : 2008 Feb

PMID : 18341256






1 Functional Relationships(s)
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1 Six AChE monooxime-monocarbamoyl reactivators with an (E)-but-2-ene linker were synthesized using modification of currently known synthetic pathways. 2-butene acetylcholinesterase (Cartwright blood group) Homo sapiens