Title : The haemotoxicity of azathioprine in repeat dose studies in the female CD-1 mouse.

Pub. Date : 2008 Apr

PMID : 18336531






1 Functional Relationships(s)
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1 At day 1 after the final dose, AZA induced a dose-related pancytopaenia, reduced femoral marrow cellularity, increases in serum levels of the cytokine fms-like tyrosine kinase 3 ligand, reduction in granulocyte-monocyte colony-forming units and erythroid colonies, and increased bone marrow apoptosis. Azathioprine FMS-like tyrosine kinase 3 ligand Mus musculus