Title : Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.

Pub. Date : 2008 Jun

PMID : 18332078






1 Functional Relationships(s)
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1 CYP3A4 and CYP2B6 induction in Fa2N-4 cells were also low for phenytoin, phenobarbital, and efavirenz, which are dual activators of PXR/CAR. Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens