Pub. Date : 2008 Jul
PMID : 18331597
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that staphylokinase (SAK), a well-known Plg activator of bacterial origin, inhibits Plg activation mediated by endogenous tPA and uPA. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |
| 2 | We found that staphylokinase (SAK), a well-known Plg activator of bacterial origin, inhibits Plg activation mediated by endogenous tPA and uPA. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |
| 3 | Furthermore, mixture of SAK with tPA led to a significantly reduced Plg-dependent fibrinolysis. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |
| 4 | Finally, we show that NH2-terminal residues of SAK are important for the inhibitory effect of SAK on tPA- and uPA-mediated Plg activation. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |
| 5 | In conclusion, SAK reduces tPA/uPA-mediated Plg activation by means of SAK.Plg complex formation, consequently downregulating tPA/uPA-induced fibrinolysis. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |
| 6 | In conclusion, SAK reduces tPA/uPA-mediated Plg activation by means of SAK.Plg complex formation, consequently downregulating tPA/uPA-induced fibrinolysis. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |
| 7 | In conclusion, SAK reduces tPA/uPA-mediated Plg activation by means of SAK.Plg complex formation, consequently downregulating tPA/uPA-induced fibrinolysis. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |
| 8 | In conclusion, SAK reduces tPA/uPA-mediated Plg activation by means of SAK.Plg complex formation, consequently downregulating tPA/uPA-induced fibrinolysis. | Tetradecanoylphorbol Acetate | plasminogen | Homo sapiens |