Pub. Date : 2008 Jul
PMID : 18330893
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | H2O2 also increased the level of p38 MAPK, JNK/SAPK, and NF-kappaB phosphorylation, which were inhibited by the DHT pretreatment. | Hydrogen Peroxide | mitogen-activated protein kinase 14 | Mus musculus |
| 2 | However, the flutamide treatment abolished the inhibitory effects of DHT on the H2O2-induced increase in the levels of p38 MAPK, JNK/SAPK, and NF-kappaB phosphorylation. | Hydrogen Peroxide | mitogen-activated protein kinase 14 | Mus musculus |
| 3 | In conclusion, DHT prevents the H2O2-induced apoptotic cell death of mouse ES cells through the activation of catalase and the downregulation of p38 MAPK, JNK/SAPK, and NF-kappaB via the androgen receptor. | Hydrogen Peroxide | mitogen-activated protein kinase 14 | Mus musculus |