Pub. Date : 2008 Oct
PMID : 18328086
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NAD(+) dependent 15-hydroxyprostaglandin dehydrogenate (15-PGDH) catalyses oxidation of 15(S)-hydroxyl group of prostaglandins and as a result inactivates their physiological potential. | Prostaglandins | 15-hydroxyprostaglandin dehydrogenase | Homo sapiens |
| 2 | In the present study, we showed that 15-PGDH was expressed in human hair follicle mainly in melanocytes and keratinocytes, which brought us to consider this enzyme as a possible target to sustain local prostaglandin production. | Prostaglandins | 15-hydroxyprostaglandin dehydrogenase | Homo sapiens |
| 3 | In the context of recent interest in prostaglandins and prostaglandin analogues as hair regrowth agents, we postulated that the use of selected 15-PGDH inhibitors could reinforce or prolong the effect of these physiological mediators on hair and skin. | Prostaglandins | 15-hydroxyprostaglandin dehydrogenase | Homo sapiens |
| 4 | In the context of recent interest in prostaglandins and prostaglandin analogues as hair regrowth agents, we postulated that the use of selected 15-PGDH inhibitors could reinforce or prolong the effect of these physiological mediators on hair and skin. | Prostaglandins | 15-hydroxyprostaglandin dehydrogenase | Homo sapiens |