Title : STAT-1 signaling in human lung fibroblasts is induced by vanadium pentoxide through an IFN-beta autocrine loop.

Pub. Date : 2008 Mar 15

PMID : 18322232






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Taken together, these data indicate that fibroblasts play a role in the innate immune response to vanadium-induced oxidative stress by synthesizing IFN-beta and activating STAT-1 to cause growth arrest and increase levels of CXCL10, a potent antifibrotic factor. Vanadium interferon beta 1 Homo sapiens