Title : Cholesterol is obligatory for polarization and chemotaxis but not for endocytosis and associated signaling from chemoattractant receptors in human neutrophils.

Pub. Date : 2008 Jul

PMID : 18311596






1 Functional Relationships(s)
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1 Here we demonstrate that cholesterol was absolutely required for polarized redistribution of key chemotactic mediators in human neutrophils in response to all chemoattractants tested (fMet-Leu-Phe, and the chemokines CXCL1, CXCL8 and CXCL12). Cholesterol C-X-C motif chemokine ligand 8 Homo sapiens