Title : Chronic morphine treatment selectively suppresses macrophage colony formation in bone marrow.

Pub. Date : 1991 Apr 3

PMID : 1831136






1 Functional Relationships(s)
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1 Incubation of bone marrow cells from untreated mice for 7 days with in vitro morphine concentrations as low as 25 microM also reduced macrophage colony formation, and the opioid peptide beta-endorphin was even more potent, significantly reducing macrophage colony formation at concentrations as low as 0.25 microM. Morphine pro-opiomelanocortin-alpha Mus musculus