Title : Differential regulation of lymphokine production in mitogen-stimulated murine spleen cells.

Pub. Date : 1991 Aug

PMID : 1831130






2 Functional Relationships(s)
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1 Activation of murine spleen cells in vitro with soluble anti-CD3 monoclonal antibody and phorbol 12-myristate 13-acetate (PMA) induced an initial production of interleukin 2 (IL2), interferon-gamma (IFN-gamma), IL4 and IL5, followed by a refractory state during which the T cells did not produce lymphokines when stimulated with some common mitogens. Tetradecanoylphorbol Acetate interleukin 4 Mus musculus
2 Activation of murine spleen cells in vitro with soluble anti-CD3 monoclonal antibody and phorbol 12-myristate 13-acetate (PMA) induced an initial production of interleukin 2 (IL2), interferon-gamma (IFN-gamma), IL4 and IL5, followed by a refractory state during which the T cells did not produce lymphokines when stimulated with some common mitogens. Tetradecanoylphorbol Acetate interleukin 4 Mus musculus