Title : Longitudinal effects of thymidine analogues on mtDNA, mtRNA and multidrug resistance (MDR-1) induction in cultured cells.

Pub. Date : 2008 May

PMID : 18310046






1 Functional Relationships(s)
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1 Our aim was to investigate the longitudinal effects of two thymidine analogue NRTIs, zidovudine and stavudine, on human cells, measuring their effects on the levels of mtDNA, mtRNA and on induction of the multidrug resistance (MDR) gene MDR-1. Zidovudine ATP binding cassette subfamily B member 1 Homo sapiens