Title : Current concepts: renin inhibition in the treatment of hypertension.

Pub. Date : 2008 Apr

PMID : 18308634






3 Functional Relationships(s)
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1 The development of aliskiren, the first orally effective renin inhibitor, utilized molecular modeling based upon X-ray crystallographic analysis of renin"s active site to design a potent, low molecular weight renin inhibitor with improved bioavailability (approximately 2.6%). aliskiren renin Homo sapiens
2 The development of aliskiren, the first orally effective renin inhibitor, utilized molecular modeling based upon X-ray crystallographic analysis of renin"s active site to design a potent, low molecular weight renin inhibitor with improved bioavailability (approximately 2.6%). aliskiren renin Homo sapiens
3 The development of aliskiren, the first orally effective renin inhibitor, utilized molecular modeling based upon X-ray crystallographic analysis of renin"s active site to design a potent, low molecular weight renin inhibitor with improved bioavailability (approximately 2.6%). aliskiren renin Homo sapiens