Title : 4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians.

Pub. Date : 2008 Mar

PMID : 18300941






2 Functional Relationships(s)
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1 4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians. cholest-5-ene-3,4-diol cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 OBJECTIVES: To study the potential endogenous marker of CYP3A activity, 4beta-hydroxycholesterol, and its relation to sex and the CYP3A5 geno/haplotypes and compare with CYP3A4/5 catalyzed 3-hydroxylation of quinine in the three major races. cholest-5-ene-3,4-diol cytochrome P450 family 3 subfamily A member 5 Homo sapiens