Title : Targeting MDR1 gene: synthesis and cellular study of modified daunomycin-triplex-forming oligonucleotide conjugates able to inhibit gene expression in resistant cell lines.

Pub. Date : 2008 May

PMID : 18299310






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The oligonucleotide moiety of the conjugate changes the cellular penetration properties of the antitumor agent that is no more the target of P-gp in resistant cells. Oligonucleotides ATP binding cassette subfamily B member 1 Homo sapiens