Pub. Date : 2008 May
PMID : 18294330
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | WHAT THIS STUDY ADDS: This study indicates that the stereoselective pharmacokinetics of fexofenadine are due to P-gp-mediated transport and its stereoselectivity is altered by itraconazole, a an inhibitor of P-gp. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | WHAT THIS STUDY ADDS: This study indicates that the stereoselective pharmacokinetics of fexofenadine are due to P-gp-mediated transport and its stereoselectivity is altered by itraconazole, a an inhibitor of P-gp. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | AIMS: The aim of this study was to determine the inhibitory effect of itraconazole, a P-glycoprotein (P-gp) inhibitor, on the stereoselective pharmacokinetics of fexofenadine. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | AIMS: The aim of this study was to determine the inhibitory effect of itraconazole, a P-glycoprotein (P-gp) inhibitor, on the stereoselective pharmacokinetics of fexofenadine. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | CONCLUSIONS: This study indicates that the stereoselective pharmacokinetics of fexofenadine are due to P-gp-mediated transport and its stereoselectivity is altered by itraconazole, a P-gp inhibitor. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | CONCLUSIONS: This study indicates that the stereoselective pharmacokinetics of fexofenadine are due to P-gp-mediated transport and its stereoselectivity is altered by itraconazole, a P-gp inhibitor. | fexofenadine | ATP binding cassette subfamily B member 1 | Homo sapiens |