Pub. Date : 1991 Feb
PMID : 1829231
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of 5-HT1A activity in the discriminative stimulus effects of imipramine. | Imipramine | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 2 | The selective 5-HT1A agonist 8-OH-DPAT (0.03-1.0 mg/kg) resulted in dose-dependent increases in responding on the key correlated with imipramine administration. | Imipramine | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 3 | The discriminative stimulus effects of imipramine were also blocked by administration of the alpha 1-adrenoceptor antagonist prazosin, suggesting a dual mediation of imipramine through both 5-HT1A and alpha 1-adrenoreceptor systems. | Imipramine | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 4 | The discriminative stimulus effects of imipramine were also blocked by administration of the alpha 1-adrenoceptor antagonist prazosin, suggesting a dual mediation of imipramine through both 5-HT1A and alpha 1-adrenoreceptor systems. | Imipramine | 5-hydroxytryptamine receptor 1A | Homo sapiens |