Title : Gonadotropin stimulation of ovarian fractalkine expression and fractalkine augmentation of progesterone biosynthesis by luteinizing granulosa cells.

Pub. Date : 2008 Jun

PMID : 18292196






2 Functional Relationships(s)
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1 In cultured granulosa cells, treatment with fractalkine augmented hCG stimulation of progesterone but not estradiol and cAMP biosynthesis with concomitant increases in transcript levels for key steroidogenic enzymes (steroidogenic acute regulatory protein, CYP11A, and 3beta-hydroxysteroid dehydrogenase). Progesterone chorionic gonadotropin subunit beta 5 Homo sapiens
2 In cultured preovulatory follicles, treatment with fractalkine also augmented progesterone production stimulated by hCG. Progesterone chorionic gonadotropin subunit beta 5 Homo sapiens