Title : Involvement of calpain and p25 of CDK5 pathway in ginsenoside Rb1's attenuation of beta-amyloid peptide25-35-induced tau hyperphosphorylation in cortical neurons.

Pub. Date : 2008 Mar 20

PMID : 18289510






1 Functional Relationships(s)
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Protein Name
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1 The cleavage of p35 to p25, mediated by calpain and calcium, caused CDK5 dislocation and subsequently p25/CDK5-induced tau hyperphosphorylation, which disrupted the cytoskeleton and resulted in neuronal death. Calcium microtubule associated protein tau Homo sapiens