Title : Sites of action of angiotensin II, atrial natriuretic factor and guanabenz, on aldosterone biosynthesis.

Pub. Date : 1991 May

PMID : 1828176






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ANF inhibits the formation of pregnenolone, the steps between progesterone and deoxycorticosterone, deoxycorticosterone and corticosterone and finally, corticosterone and aldosterone with ED50 of 114 +/- 17, 199 +/- 90, 14 +/- 3 and 92 +/- 34 pM of ANF, respectively, and around 70% of inhibition. Progesterone natriuretic peptide A Homo sapiens