Title : Synthesis and preliminary biological evaluation of new carbon-11 labeled tetrahydroisoquinoline derivatives as SERM radioligands for PET imaging of ER expression in breast cancer.

Pub. Date : 2008 Oct

PMID : 18272256






1 Functional Relationships(s)
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Protein Name
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1 Tetrahydroisoquinoline derivatives are a class of selective estrogen receptor modulators (SERMs) with high binding affinity and specificity exhibiting up to 50 folds for ERalpha over ERbeta. 1,2,3,4-tetrahydroisoquinoline estrogen receptor 1 Homo sapiens