Title : Novel sulfonanilide analogs decrease aromatase activity in breast cancer cells: synthesis, biological evaluation, and ligand-based pharmacophore identification.

Pub. Date : 2008 Mar 13

PMID : 18271519






1 Functional Relationships(s)
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1 Previously, the COX-2 selective inhibitor nimesulide and analogs decreased aromatase expression and enzyme activity independent of COX-2 inhibition. nimesulide mitochondrially encoded cytochrome c oxidase II Homo sapiens