Title : Use of radiolabeled monoclonal antibody to enhance vaccine-mediated antitumor effects.

Pub. Date : 2008 Aug

PMID : 18256832






1 Functional Relationships(s)
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1 A single dose of Y-90-labeled anti-CEA mAb, in combination with vaccine therapy, resulted in a statistically significant increase in survival in tumor-bearing mice over vaccine or mAb alone; this was shown to be mediated by engagement of the Fas/Fas ligand pathway. Yttrium-90 CEA cell adhesion molecule 3 Homo sapiens