Title : Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells.

Pub. Date : 2008 Sep

PMID : 18248652






1 Functional Relationships(s)
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1 CONCLUSION: Exposure of leiomyomas to ATRA down-regulated cell proliferation, ECM formation, RA metabolism and TGF-beta regulation, suggesting that RA exposure can alter the leiomyoma phenotype to one that more closely approximates normal myometrium. Tretinoin transforming growth factor beta 1 Homo sapiens