Title : Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.

Pub. Date : 2008 Mar

PMID : 18245810






1 Functional Relationships(s)
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1 In vitro studies showed that AngII induced the down-regulation of both nephrin and WT-1 expression in podocytes, which was reversed by fasudil in a dose-dependent manner. fasudil WT1 transcription factor Mus musculus