Title : The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia.

Pub. Date : 2008 Mar 17

PMID : 18242596






1 Functional Relationships(s)
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1 Animals dosed with CP-690550 (15 mg/kg/d) during the period of antigen sensitization and boost demonstrated marked reductions in BAL eosinophils and levels of IL-13 and eotaxin following ovalbumin aerosol exposure. tofacitinib chemokine (C-C motif) ligand 11 Mus musculus