Title : Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts.

Pub. Date : 2008 Feb

PMID : 18240216






1 Functional Relationships(s)
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1 Blocking platelet-derived growth factor receptor with Gleevec (imatinib mesylate) reduced overall contractile ability and the elevated syndecan 4 expression and ERK activation in SSc fibroblasts. Imatinib Mesylate mitogen-activated protein kinase 1 Homo sapiens