Pub. Date : 1991
PMID : 1823389
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Evaluation of insulin-induced changes in the renal response to furosemide in normal subjects. | Furosemide | insulin | Homo sapiens |
| 2 | We analyzed the response of the kidney to furosemide in 5 healthy men, in the presence of both normal physiological serum insulin levels and levels at the upper limit of the physiological range, obtained by the hyperinsulinemic-euglycemic clamp technique. | Furosemide | insulin | Homo sapiens |
| 3 | After furosemide administration, glomerular filtration rate, urine flow, urine sodium excretion, free water clearance, urine pH, plasma renin activity and plasma aldosterone exhibited the same behavior in the presence of both serum insulin concentrations. | Furosemide | insulin | Homo sapiens |
| 4 | The rise in urinary potassium excretion following furosemide administration was significantly lower in the presence of high insulin concentrations. | Furosemide | insulin | Homo sapiens |
| 5 | Thus, in conditions in which natriuresis is mildly stimulated, as in the case of the administration of low doses of furosemide, insulin does not affect the rate of renal sodium reabsorption. | Furosemide | insulin | Homo sapiens |