Title : p53-, SIRT1-, and PARP-1-independent downregulation of p21WAF1 expression in nicotinamide-treated cells.

Pub. Date : 2008 Apr 4

PMID : 18230337






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 p53-, SIRT1-, and PARP-1-independent downregulation of p21WAF1 expression in nicotinamide-treated cells. Niacinamide tumor protein p53 Homo sapiens
2 In our study, the treatment of 10mM nicotinamide downregulated p21WAF1 expression in various human cells including p53-negative or SIRT1-knockdown cells indicating gene regulation not mediated by p53 or SIRT1. Niacinamide tumor protein p53 Homo sapiens
3 In our study, the treatment of 10mM nicotinamide downregulated p21WAF1 expression in various human cells including p53-negative or SIRT1-knockdown cells indicating gene regulation not mediated by p53 or SIRT1. Niacinamide tumor protein p53 Homo sapiens