Title : Inhibition of tau aggregation in cell models of tauopathy.

Pub. Date : 2007 Dec

PMID : 18220518






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the cell models the repeat domain of tau (tau(RD)) and some of its variants are expressed in a regulated fashion, e.g. the 4-repeat domain of tau with the wild-type sequence, the repeat domain with the deltaK280 mutation ("pro-aggregation mutant"), or the repeat domain with additional proline mutations ("anti-aggregation mutant"). Proline microtubule associated protein tau Homo sapiens
2 In the cell models the repeat domain of tau (tau(RD)) and some of its variants are expressed in a regulated fashion, e.g. the 4-repeat domain of tau with the wild-type sequence, the repeat domain with the deltaK280 mutation ("pro-aggregation mutant"), or the repeat domain with additional proline mutations ("anti-aggregation mutant"). Proline microtubule associated protein tau Homo sapiens
3 In the cell models the repeat domain of tau (tau(RD)) and some of its variants are expressed in a regulated fashion, e.g. the 4-repeat domain of tau with the wild-type sequence, the repeat domain with the deltaK280 mutation ("pro-aggregation mutant"), or the repeat domain with additional proline mutations ("anti-aggregation mutant"). Proline microtubule associated protein tau Homo sapiens