Title : Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells.

Pub. Date : 2008 Jun

PMID : 18218921






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This appears to be a direct effect of FGF signaling through mitogen-activated protein kinase (MAPK) cascades as the treatment of VICs with the MAPK/extracellular regulated kinase (MEK) inhibitor U0126 acted to induce fibrosis and blocked the ability of FGF-2 to inhibit TGF-beta1 signaling. U 0126 transforming growth factor beta 1 Homo sapiens