Title : The 7-amino-acid site in the proline-rich region of the N-terminal domain of p53 is involved in the interaction with FAK and is critical for p53 functioning.

Pub. Date : 2008 Apr 1

PMID : 18215142






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The 7-amino-acid site in the proline-rich region of the N-terminal domain of p53 is involved in the interaction with FAK and is critical for p53 functioning. Proline protein tyrosine kinase 2 Homo sapiens
2 In the present study, using phage display, sitedirected mutagenesis, pulldown and immunoprecipitation assays we localized the site of FAK binding to a 7-amino-acid region(amino acids 65-71) in the N-terminal proline-rich domain of human p53. Proline protein tyrosine kinase 2 Homo sapiens