Pub. Date : 2008 Jan
PMID : 18202020
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The z-guggulsterone-mediated inhibition of angiogenesis in vitro correlated with the suppression of secretion of proangiogenic growth factors [e.g., vascular endothelial growth factor (VEGF) and granulocyte colony-stimulating factor], down-regulation of VEGF receptor 2 (VEGF-R2) protein level, and inactivation of Akt. | pregna-4,17-diene-3,16-dione | vascular endothelial growth factor A | Homo sapiens |
| 2 | The z-guggulsterone-mediated inhibition of angiogenesis in vitro correlated with the suppression of secretion of proangiogenic growth factors [e.g., vascular endothelial growth factor (VEGF) and granulocyte colony-stimulating factor], down-regulation of VEGF receptor 2 (VEGF-R2) protein level, and inactivation of Akt. | pregna-4,17-diene-3,16-dione | vascular endothelial growth factor A | Homo sapiens |
| 3 | In conclusion, the present study reveals that z-guggulsterone inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis. | pregna-4,17-diene-3,16-dione | vascular endothelial growth factor A | Homo sapiens |
| 4 | In conclusion, the present study reveals that z-guggulsterone inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis. | pregna-4,17-diene-3,16-dione | vascular endothelial growth factor A | Homo sapiens |