Pub. Date : 2008 Apr 1
PMID : 18201741
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The goal of the present study was to determine the role of JNK pathway signaling for regulating B-cell apoptosis in two important but contrasting situations--global proteotoxic damage, induced by arsenite and hyperthermia, versus specific microtubule inhibition, induced by the anti-cancer drug vincristine, using the EW36 B-cell line. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |
2 | Exposure of EW36 B-cells to arsenite or lethal hyperthermia resulted in activation of the JNK pathway and induction of apoptosis. | arsenite | mitogen-activated protein kinase 8 | Homo sapiens |