Pub. Date : 2008 Apr
PMID : 18199701
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, using a cellular model of HD, we found that rapamycin significantly decreased aggregation-prone polyglutamine (polyQ) and expanded huntingtin and its inclusion bodies (IB) in both autophagy-proficient and autophagy-deficient cells (by genetic knockout of the atg5 gene in mouse embryonic fibroblasts). | Sirolimus | huntingtin | Mus musculus |