Title : Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic beta-cell.

Pub. Date : 2008 Jul

PMID : 18191448






1 Functional Relationships(s)
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1 We hypothesize that the improvement of glucose-stimulated insulin secretion by sulfonylurea compounds in type 2 diabetic patients is in part due to their capacity to raise mitochondrial calcium, which is beneficial for the generation of metabolic coupling factors. Sulfonylurea Compounds insulin Homo sapiens