Title : [Regulating human interferon-gamma gene expression in marrow stromal cells in mice by Tet-off system].

Pub. Date : 2008 Jan

PMID : 18184463






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1 [Regulating human interferon-gamma gene expression in marrow stromal cells in mice by Tet-off system]. tetramethylenedisulfotetramine interferon gamma Homo sapiens
2 BACKGROUND & OBJECTIVE: We have constructed plasmid "pTre-IFN-gamma" and proved that the Tet-off system could regulate the expression of human interferon-gamma (IFN-gamma) gene in murine marrow stromal cells in vitro. tetramethylenedisulfotetramine interferon gamma Homo sapiens
3 BACKGROUND & OBJECTIVE: We have constructed plasmid "pTre-IFN-gamma" and proved that the Tet-off system could regulate the expression of human interferon-gamma (IFN-gamma) gene in murine marrow stromal cells in vitro. tetramethylenedisulfotetramine interferon gamma Homo sapiens
4 BACKGROUND & OBJECTIVE: We have constructed plasmid "pTre-IFN-gamma" and proved that the Tet-off system could regulate the expression of human interferon-gamma (IFN-gamma) gene in murine marrow stromal cells in vitro. tetramethylenedisulfotetramine interferon gamma Homo sapiens
5 This study was to investigate the regulatory reversibility of Tet-off system and its effect on the expression of human IFN-gamma gene in murine marrow stromal cells in mice. tetramethylenedisulfotetramine interferon gamma Homo sapiens
6 CONCLUSION: In mice, Tet-off system could rapidly, efficiently and reversibly regulate the expression of human IFN-gamma gene in marrow stromal cells in vitro and in vivo. tetramethylenedisulfotetramine interferon gamma Homo sapiens