Pub. Date : 2008 Jan 1
PMID : 18172297
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Experiments using small interfering RNA-mediated knockdown indicate that this activation is mediated by Rap1, which is activated by a TPA-responsive guanine nucleotide exchange factor RasGRP3. | Tetradecanoylphorbol Acetate | RAS-related protein 1a | Mus musculus |
| 2 | Moreover, TPA-induced activation of Rap1 and PLC epsilon is inhibited by a PKC inhibitor GF109203X, indicating a crucial role of PKC in signaling from TPA to PLC epsilon. | Tetradecanoylphorbol Acetate | RAS-related protein 1a | Mus musculus |
| 3 | Moreover, TPA-induced activation of Rap1 and PLC epsilon is inhibited by a PKC inhibitor GF109203X, indicating a crucial role of PKC in signaling from TPA to PLC epsilon. | Tetradecanoylphorbol Acetate | RAS-related protein 1a | Mus musculus |