Title : Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein.

Pub. Date : 2008 Feb 15

PMID : 18164724






2 Functional Relationships(s)
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1 Experiments were designed to detect possible conformational changes that occur when LacI binds either DNA or the inducer IPTG, or both. Isopropyl Thiogalactoside tissue factor pathway inhibitor Homo sapiens
2 The binding of IPTG to native (tetrameric) LacI-oDNA complexes also appears to facilitate a modest change in the average homodimer-homodimer disposition. Isopropyl Thiogalactoside tissue factor pathway inhibitor Homo sapiens