Title : Id-1 regulates Bcl-2 and Bax expression through p53 and NF-kappaB in MCF-7 breast cancer cells.

Pub. Date : 2008 Nov

PMID : 18158619






1 Functional Relationships(s)
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1 Taken together, we present a molecular mechanism where Id-1 regulates p53 and NF-kappaB pathways, which in turn regulates Bax and Bcl-2 genes, thus providing a survival advantage under exogenous stress such as serum-free or taxol treatment in MCF-7 breast cancer cells. Paclitaxel tumor protein p53 Homo sapiens