Title : Antithrombin activity and disaccharide composition of dermatan sulfate from different bovine tissues.

Pub. Date : 2008 Mar

PMID : 18156656






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Dermatan sulfate is a glycosaminoglycan that selectively inhibits the action of thrombin through interaction with heparin cofactor II. Dermatan Sulfate serpin family D member 1 Bos taurus
2 Previous studies have showed that dermatan sulfate derived from porcine/bovine intestinal mucosa/skin or marine invertebrates is capable of stimulating heparin cofactor II-mediated thrombin inhibition in vitro. Dermatan Sulfate serpin family D member 1 Bos taurus
3 Heparin cofactor II/dermatan sulfate-mediated thrombin inhibition measured in vitro revealed activity comparable to or higher than the commercial standard with 2-fold differences observed between some tissues. Dermatan Sulfate serpin family D member 1 Bos taurus