Title : Antidepressant and other centrally acting drugs regulate glucocorticoid receptor messenger RNA levels in rat brain.

Pub. Date : 1991

PMID : 1811246






4 Functional Relationships(s)
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1 Northern blot analysis of Type II GR mRNA showed that treatment of male rats with either desipramine or imipramine increased hypothalamic and hippocampal GR mRNA levels. Desipramine nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus
2 Northern blot analysis of Type II GR mRNA showed that treatment of male rats with either desipramine or imipramine increased hypothalamic and hippocampal GR mRNA levels. Desipramine nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus
3 We conclude that desipramine, imipramine, ketanserin and lithium can modulate GR mRNA in regions of rat brain involved in the control of the HPA axis and may have a common mechanism of action at the level of the GR gene. Desipramine nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus
4 We conclude that desipramine, imipramine, ketanserin and lithium can modulate GR mRNA in regions of rat brain involved in the control of the HPA axis and may have a common mechanism of action at the level of the GR gene. Desipramine nuclear receptor subfamily 3, group C, member 1 Rattus norvegicus