Title : Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism.

Pub. Date : 2007 Dec

PMID : 18096507






3 Functional Relationships(s)
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1 Pretreatment with calyculin A, an inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A), blocked emetine-induced alternative splicing in contrast to okadaic acid, a specific inhibitor of PP2A in cells, demonstrating a PP1-mediated mechanism. Emetine protein phosphatase 2 phosphatase activator Homo sapiens
2 Pretreatment with calyculin A, an inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A), blocked emetine-induced alternative splicing in contrast to okadaic acid, a specific inhibitor of PP2A in cells, demonstrating a PP1-mediated mechanism. Emetine protein phosphatase 2 phosphatase activator Homo sapiens
3 Pretreatment with calyculin A, an inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A), blocked emetine-induced alternative splicing in contrast to okadaic acid, a specific inhibitor of PP2A in cells, demonstrating a PP1-mediated mechanism. Emetine protein phosphatase 2 phosphatase activator Homo sapiens