Pub. Date : 2008 Jun
PMID : 18096419
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We suggest that the small hydrophobic substituents at C-6 position of pyrrolopyrazole nucleus (in compounds 1-8); C-6 and C-7 positions of the quinazoline moiety (in compounds 9-23); C-2 position of the quinazoline and C-4 position of the pyrimidine (in compound 25) could be more effective and selective through increased hydrophobic contacts and selectivity pocket interactions with these modifications of Aurora A kinase inhibitors. | pyrimidine | complement C2 | Homo sapiens |