Pub. Date : 2008 Mar
PMID : 18094064
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We previously showed in conscious piglets that activation of 5-HT1A receptors with (+/-)-8-hydroxy-2-(dipropylamino)-tetralin (8-OH-DPAT) in the paragigantocellularis lateralis (PGCL), a medullary region lateral to the raphe that contains substantial numbers of 5-HT neurons, eliminates rapid eye movement (REM) sleep and decreases shivering in a cold environment, but does not attenuate peripheral vasoconstriction. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 2 | We previously showed in conscious piglets that activation of 5-HT1A receptors with (+/-)-8-hydroxy-2-(dipropylamino)-tetralin (8-OH-DPAT) in the paragigantocellularis lateralis (PGCL), a medullary region lateral to the raphe that contains substantial numbers of 5-HT neurons, eliminates rapid eye movement (REM) sleep and decreases shivering in a cold environment, but does not attenuate peripheral vasoconstriction. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine receptor 1A | Homo sapiens |
| 3 | The effects of 8-OH-DPAT were prevented after dialysis of the selective 5-HT1A receptor antagonist WAY-100635. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine receptor 1A | Homo sapiens |