Title : Restoration of CREB function ameliorates cisplatin cytotoxicity in renal tubular cells.

Pub. Date : 2008 Mar

PMID : 18094030






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CREB-mediated transcription as well as survival was restored by the histone deacetylase (HDAC) inhibitor trichostatine A (TSA), an effective chemotherapeutic agent. trichostatin A cAMP responsive element binding protein 1 Mus musculus
2 CREB-mediated transcription as well as survival was restored by the histone deacetylase (HDAC) inhibitor trichostatine A (TSA), an effective chemotherapeutic agent. trichostatin A cAMP responsive element binding protein 1 Mus musculus
3 Similar to severe oxidant stress, TSA-mediated survival could be abrogated by inhibition of CREB-mediated transcription. trichostatin A cAMP responsive element binding protein 1 Mus musculus