Title : Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.

Pub. Date : 2008 Mar

PMID : 18089838






1 Functional Relationships(s)
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1 TCDD-mediated inductions of various AhR targets, such as the drug metabolizing CYP1B1, the cytokine interleukin-1beta, the chemokines interleukin-8 and CCL1, the adhesion molecule beta7 integrin, and the AhR repressor, were also prevented by KN-93 in human macrophages. Polychlorinated Dibenzodioxins cytochrome P450 family 1 subfamily B member 1 Homo sapiens