Pub. Date : 2007 Dec
PMID : 18088462
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [STI571 induces apoptosis of K562 cells through down-regulation of anti-apoptotic protein Mcl-1 and Bcl-xl expression]. | Imatinib Mesylate | BCL2 like 1 | Homo sapiens |
| 2 | It is concluded that STI571 induces the apoptosis of CML cells by down-regulating the expressions of Mcl-1 and Bcl-xl, which suggests that Mcl-1 and Bcl-xl may play an important role in anti-apoptotic process of CML cells. | Imatinib Mesylate | BCL2 like 1 | Homo sapiens |
| 3 | It is concluded that STI571 induces the apoptosis of CML cells by down-regulating the expressions of Mcl-1 and Bcl-xl, which suggests that Mcl-1 and Bcl-xl may play an important role in anti-apoptotic process of CML cells. | Imatinib Mesylate | BCL2 like 1 | Homo sapiens |